Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells.

@article{Majumdar1998PhenotypicAF,
  title={Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells.},
  author={Manas K. Majumdar and Mark A. Thiede and Joseph D. Mosca and M. Moorman and Stanton L. Gerson},
  journal={Journal of cellular physiology},
  year={1998},
  volume={176 1},
  pages={57-66}
}
Mesenchymal stem cells (MSCs) are a population of pluripotent cells within the bone marrow microenvironment defined by their ability to differentiate into cells of the osteogenic, chondrogenic, tendonogenic, adipogenic, and myogenic lineages. We have developed methodologies to isolate and culture-expand MSCs from human bone marrow, and in this study, we examined the MSC's role as a stromal cell precursor capable of supporting hematopoietic differentiation in vitro. We examined the morphology… CONTINUE READING
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