Phenotypic analysis of the inflammatory exudate in murine lymphocytic choriomeningitis

@article{Ceredig1987PhenotypicAO,
  title={Phenotypic analysis of the inflammatory exudate in murine lymphocytic choriomeningitis},
  author={Rhodri Ceredig and Jane E. Allan and Z Tabi and Frank Lynch and Peter C. Doherty},
  journal={The Journal of Experimental Medicine},
  year={1987},
  volume={165},
  pages={1539 - 1551}
}
The massive inflammation of the cerebrospinal fluid (CSF) which occurs in adult mice injected with lymphocytic choriomeningitis virus (LCMV) has been analyzed by flow microfluorometry (FMF). The great majority of the T cells detected by direct examination of freshly obtained CSF were found to be Lyt-2+, with an almost total absence of L3T4+ lymphocytes. The Lyt-2/L3T4 ratio of lymphocytes in blood was within normal limits. Predominance of the Lyt-2+ subset was confirmed by culturing the CSF… CONTINUE READING
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