Phenotypic analysis of ovarian carcinoma: polypeptide expression in benign, borderline and malignant tumors.

@article{Alaiya1997PhenotypicAO,
  title={Phenotypic analysis of ovarian carcinoma: polypeptide expression in benign, borderline and malignant tumors.},
  author={Ayodele A. Alaiya and Bo Franz{\'e}n and Kaoru Fujioka and Birgitta Moberger and Kjell Schedvins and C Silfversv{\"a}rd and Stig Linder and Gert Auer},
  journal={International journal of cancer},
  year={1997},
  volume={73 5},
  pages={678-83}
}
Studies of multiple markers in tumors are required for adequate biological characterization. We have characterized the expression of multiple proteins in human ovarian tumors using the technique of 2-dimensional gel electrophoresis (2-DE/PDQUEST). Tumor cells were prepared from the tissue of 22 ovarian tumors. Large variations were observed between tumors in the expression of various polypeptides, indicating heterogeneity in gene expression. An increase in the spot density of 2 cell-cycle… CONTINUE READING

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