Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2).

@article{Gottsch2005PhenotypicAO,
  title={Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2).},
  author={Michelle L. Gottsch and Hongkui Zeng and John G. Hohmann and David Weinshenker and Donald K. Clifton and Robert A Steiner},
  journal={Molecular and cellular biology},
  year={2005},
  volume={25 11},
  pages={4804-11}
}
Galanin is a neuropeptide implicated in the regulation of feeding, reproduction, cognition, nociception, and seizure susceptibility. There are three known galanin receptor (GALR) subtypes (GALR1, GALR2, and GALR3), which bind to galanin with different affinities and have their own unique distributions, signaling mechanisms, and putative functions in the brain and peripheral nervous system. To gain further insight into the possible physiological significance of GALR2, we created mutant mice that… CONTINUE READING
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