Phenotypic Resistance and the Dynamics of Bacterial Escape from Phage Control

@inproceedings{Bull2014PhenotypicRA,
  title={Phenotypic Resistance and the Dynamics of Bacterial Escape from Phage Control},
  author={J. J. Bull and Christina Skovgaard Vegge and Matthew W Schmerer and Waqas Nasir Chaudhry and Bruce R. Levin},
  booktitle={PloS one},
  year={2014}
}
The canonical view of phage - bacterial interactions in dense, liquid cultures is that the phage will eliminate most of the sensitive cells; genetic resistance will then ascend to restore high bacterial densities. Yet there are various mechanisms by which bacteria may remain sensitive to phages but still attain high densities in their presence - because bacteria enter a transient state of reduced adsorption. Importantly, these mechanisms may be cryptic and inapparent prior to the addition of… CONTINUE READING
Highly Cited
This paper has 51 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

51 Citations

010203020142015201620172018
Citations per Year
Semantic Scholar estimates that this publication has 51 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Resource-limited growth, competition, and predation – a model and experimental studies with bacteria and bacteriophage

  • BR Levin, FM Stewart, L Chao
  • American Naturalist
  • 1977
Highly Influential
8 Excerpts

Conditions for the existence of bacteriophage

  • A Campbell
  • Evolution
  • 1961
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…