Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm

@inproceedings{Alhede2011PhenotypesON,
  title={Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm},
  author={Morten Alhede and Kasper N Kragh and Klaus Qvortrup and Marie Allesen-Holm and Maria van Gennip and Louise Dahl Christensen and Peter {\O}strup Jensen and Anne Kathrine Nielsen and Matt Parsek and D. B. Wozniak and S{\o}ren Molin and Tim Tolker-Nielsen and Niels H{\o}iby and Michael Givskov and Thomas Bjarnsholt},
  booktitle={PloS one},
  year={2011}
}
For a chronic infection to be established, bacteria must be able to cope with hostile conditions such as low iron levels, oxidative stress, and clearance by the host defense, as well as antibiotic treatment. It is generally accepted that biofilm formation facilitates tolerance to these adverse conditions. However, microscopic investigations of samples isolated from sites of chronic infections seem to suggest that some bacteria do not need to be attached to surfaces in order to establish chronic… CONTINUE READING

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