Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells.

@article{Shi2008PhenotypeSB,
  title={Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells.},
  author={Guangpu Shi and Catherine A. Cox and Barbara P. Vistica and Cuiyan Tan and Eric Wawrousek and Igal Gery},
  journal={Journal of immunology},
  year={2008},
  volume={181 10},
  pages={7205-13}
}
Th1 and Th17 cells are characterized by their expression of IFN-gamma or IL-17, respectively. The finding of Th cells producing both IL-17 and IFN-gamma suggested, however, that certain Th cells may modify their selective cytokine expression. In this study, we examined changes in cytokine expression in an experimental system in which polarized Th1 or Th17… CONTINUE READING