Phenotype and secretory responses to oxidative stress in microglia.

@article{Pathipati2013PhenotypeAS,
  title={Phenotype and secretory responses to oxidative stress in microglia.},
  author={Praneeti Pathipati and Sebastian B Mueller and Xiangning Jiang and D M Ferriero},
  journal={Developmental neuroscience},
  year={2013},
  volume={35 2-3},
  pages={241-54}
}
The neonatal brain is particularly susceptible to oxidative stress. Our group has previously shown that following hypoxic-ischemic injury, hydrogen peroxide (H2O2) levels rise significantly particularly in the neonatal brain and are sustained for up to 7 days. This rapidly accumulated H2O2 is detrimental in the iron-rich immature brain as it can lead to the… CONTINUE READING