Phenotype and function of dendritic cells of patients with systemic lupus erythematosus.

  title={Phenotype and function of dendritic cells of patients with systemic lupus erythematosus.},
  author={Jos{\'e} Carlos Crisp{\'i}n and Mar{\'i}a In{\'e}s Vargas-Rojas and Adriana Monsiv{\'a}is-Urenda and Jorge Alcocer-Varela},
  journal={Clinical immunology},
  volume={143 1},
Dendritic cells (DC) regulate the activation and differentiation of T cells. They are activated by signals of inflammation and tissue damage, and thus could play a role in the amplification and perpetuation of autoimmune diseases such as systemic lupus erythematosus (SLE). Here we analyzed the phenotype of circulating DC from patients with SLE and studied their differentiation from monocytes. Peripheral blood DC exhibited increased levels of activation in patients with SLE. Although their in… CONTINUE READING


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