Phenotype and function of a CD56+ peripheral blood monocyte

@article{Sconocchia2005PhenotypeAF,
  title={Phenotype and function of a CD56+ peripheral blood monocyte},
  author={Giuseppe Sconocchia and Keyvan Keyvanfar and Frank El Ouriaghli and Markus Grube and K Rezvani and Hitoshi Fujiwara and J. Philip McCoy and Nancy Fern Hensel and A. J. Barrett},
  journal={Leukemia},
  year={2005},
  volume={19},
  pages={69-76}
}
G-CSF primed CD34 cells cultured for 2–3 weeks in IL-2 and stem cell factor generate CD56high cells with phenotypic and morphologic features of NK cells, and a novel adherent CD56low CD16− population expressing myeloid markers (CD33 and HLA-DR). We hypothesized that similar cells might also occur in peripheral blood. In 13/13 normal individuals, we found a circulating population of CD56low, CD33+, FcγRI+, FcγRII+, HLA-DR+, CD11bhigh, CD14+ monocytes closely resembling the cultured CD56lowCD33… CONTINUE READING
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