Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA.

Abstract

Nucleosides and 2'-deoxyribonucleoside triphosphates (dNTPs) bearing phenothiazine (PT) attached to a nucleobase (cytosine or 7-deazaadenine) either directly or through an acetylene linker were prepared through Suzuki or Sonogashira cross-coupling and triphosphorylation, and were studied as building blocks for polymerase construction of modified DNA. The… (More)
DOI: 10.1039/c7ob01439b

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