Phenomenological modelling of second cancer incidence for radiation treatment planning.

@article{Pfaffenberger2009PhenomenologicalMO,
  title={Phenomenological modelling of second cancer incidence for radiation treatment planning.},
  author={Asja Pfaffenberger and Uwe Schneider and Bj{\"o}rn Poppe and Uwe Oelfke},
  journal={Zeitschrift fur medizinische Physik},
  year={2009},
  volume={19 4},
  pages={236-50}
}
It is still an unanswered question whether a relatively low dose of radiation to a large volume or a higher dose to a small volume produces the higher cancer incidence. This is of interest in view of modalities like IMRT or rotation therapy where high conformity to the target volume is achieved at the cost of a large volume of normal tissue exposed to radiation. Knowledge of the shape of the dose response for radiation-induced cancer is essential to answer the question of what risk of second… CONTINUE READING