Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia.

@article{Volkow1987PhenomenologicalCO,
  title={Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia.},
  author={Nora D. Volkow and Alfred P. Wolf and Patrick Van Gelder and Jonathan D. Brodie and John E. Overall and Robert Cancro and F Gomez-Mont},
  journal={The American journal of psychiatry},
  year={1987},
  volume={144 2},
  pages={151-8}
}
Using [11C]-deoxy-D-glucose and positron emission tomography (PET), the authors measured brain metabolism in 18 patients with chronic schizophrenia to assess which of the metabolic measures from two test conditions was more closely related to the patients' differing clinical characteristics. The two conditions were resting and activation, and an eye tracking task was used. Patients with more negative symptoms showed lower global metabolic rates and more severe hypofrontality than did the… CONTINUE READING