Phenoloxidase is an important component of the defense against Aeromonas hydrophila Infection in a crustacean, Pacifastacus leniusculus.

@article{Liu2007PhenoloxidaseIA,
  title={Phenoloxidase is an important component of the defense against Aeromonas hydrophila Infection in a crustacean, Pacifastacus leniusculus.},
  author={Haipeng Liu and Pikul Jiravanichpaisal and Lage Cerenius and Bok Luel Lee and Irene S{\"o}derh{\"a}ll and Kenneth S{\"o}derh{\"a}ll},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 46},
  pages={
          33593-8
        }
}
The melanization cascade, in which phenoloxidase is the terminal enzyme, appears to play a key role in recognition of and defense against microbial infections in invertebrates. Here, we show that phenoloxidase activity and melanization are important for the immune defense toward a highly pathogenic bacterium, Aeromonas hydrophila, in the freshwater crayfish, Pacifastacus leniusculus. RNA interference-mediated depletion of crayfish prophenoloxidase leads to increased bacterial growth, lower… CONTINUE READING

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