Phenoloxidase Activity Acts as a Mosquito Innate Immune Response against Infection with Semliki Forest Virus

Abstract

Several components of the mosquito immune system including the RNA interference (RNAi), JAK/STAT, Toll and IMD pathways have previously been implicated in controlling arbovirus infections. In contrast, the role of the phenoloxidase (PO) cascade in mosquito antiviral immunity is unknown. Here we show that conditioned medium from the Aedes albopictus-derived… (More)
DOI: 10.1371/journal.ppat.1002977

Topics

7 Figures and Tables

Cite this paper

@inproceedings{RodriguezAndres2012PhenoloxidaseAA, title={Phenoloxidase Activity Acts as a Mosquito Innate Immune Response against Infection with Semliki Forest Virus}, author={Julio Rodriguez-Andres and Seema Rani and Margus Varjak and Margo E. Chase-Topping and Markus H. Beck and Mhairi C. Ferguson and Esther Schnettler and Rennos Fragkoudis and Gerald Barry and Andres Merits and John K. Fazakerley and Michael R Strand and Alain Kohl}, booktitle={PLoS pathogens}, year={2012} }