Phenolics from commercialized grape extracts prevent early atherosclerotic lesions in hamsters by mechanisms other than antioxidant effect.

@article{Auger2004PhenolicsFC,
  title={Phenolics from commercialized grape extracts prevent early atherosclerotic lesions in hamsters by mechanisms other than antioxidant effect.},
  author={Cyril Auger and Peggy G{\'e}rain and Florence Laurent-Bichon and Karine Portet and Aur{\'e}lie Bornet and Bertrand Caporiccio and Gerard H. Cros and P. -L. Teiss{\`e}dre and J F Rouanet},
  journal={Journal of agricultural and food chemistry},
  year={2004},
  volume={52 16},
  pages={5297-302}
}
The aim of this study was to evaluate the antiatherosclerotic effect of commercially available phenolic-rich extracts from grape seeds (ExGrape seeds, EGS; grape seed extract, GSE) and marc (ExGrape total, EGT) in cholesterol-fed hamsters and to investigate possible operating mechanisms. These extracts fed at a moderate dose mimicking two glasses of red wine per meal reduced plasma cholesterol (-11% on average) but did not affect plasma antioxidant capacity of hamsters. The extracts prevented… CONTINUE READING

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