Phenol sulfotransferase in humans: properties, regulation, and function.

@article{Weinshilboum1986PhenolSI,
  title={Phenol sulfotransferase in humans: properties, regulation, and function.},
  author={Richard M. Weinshilboum},
  journal={Federation proceedings},
  year={1986},
  volume={45 8},
  pages={
          2223-8
        }
}
Phenol sulfotransferase (PST) catalyzes the sulfate conjugation of phenolic and catechol drugs and neurotransmitters. All human tissues that have been studied in detail contain at least two forms of PST. One form is thermolabile (TL), catalyzes the sulfate conjugation of micromolar concentrations of dopamine and other phenolic monoamines, and is relatively resistant to inhibition by 2,6-dichloro-4-nitrophenol (DCNP). The other form is thermostable (TS), catalyzes the sulfate conjugation of… CONTINUE READING

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