Corpus ID: 26699230

Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug.

@article{Lapin2001PhenibutA,
  title={Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug.},
  author={I. P. Lapin},
  journal={CNS drug reviews},
  year={2001},
  volume={7 4},
  pages={
          471-81
        }
}
  • I. Lapin
  • Published 2001
  • Medicine
  • CNS drug reviews
Phenibut (beta-phenyl-gamma-aminobutyric acid HCl) is a neuropsychotropic drug that was discovered and introduced into clinical practice in Russia in the 1960s. It has anxiolytic and nootropic (cognition enhancing) effects. It acts as a GABA-mimetic, primarily at GABA(B) and, to some extent, at GABA(A) receptors. It also stimulates dopamine receptors and antagonizes beta-phenethylamine (PEA), a putative endogenous anxiogenic. The psychopharmacological activity of phenibut is similar to that of… Expand
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