Phenazopyridine-Induced Sulfhemoglobinemia

  title={Phenazopyridine-Induced Sulfhemoglobinemia},
  author={Anuradha S Gopalachar and Venita L Bowie and P. Bharadwaj},
  journal={Annals of Pharmacotherapy},
  pages={1128 - 1130}
  • Anuradha S Gopalachar, Venita L Bowie, P. Bharadwaj
  • Published 2005
  • Medicine
  • Annals of Pharmacotherapy
  • OBJECTIVE: To report a case of sulfhemoglobinemia in a patient receiving phenazopyridine for a urinary tract infection. CASE SUMMARY: A 63-year-old white woman presented to the emergency department with complaints of fatigue and bluish discoloration of her body that had gradually progressed over the previous 6–8 weeks. About 4 months prior to presenting to the emergency department, she had started taking phenazopyridine, an over-the-counter medication for symptoms of dysuria. Because the… CONTINUE READING
    26 Citations
    Topical Benzocaine and Methemoglobinemia.
    • 2
    Identification of sulfhemoglobinemia after surgical polypectomy
    • 5
    Acrocyanosis from phenazopyridine-induced sulfhemoglobinemia mistaken for Raynaud phenomenon.
    • 6


    Methemoglobinemia and sulfhemoglobinemia.
    • C. Finch
    • Medicine
    • The New England journal of medicine
    • 1948
    • 182
    Methemoglobinemia: etiology, pharmacology, and clinical management.
    • 563
    Methodologic problems encountered with cooximetry in methemoglobinemia.
    • 32
    Hemoglobin pigments. Spectrophotometric determination of oxy-, carboxy-, met-, and sulfhemoglobin in capillary blood.
    • 97
    Sulfhemoglobinemia. Clinical and molecular aspects.
    • 72
    A method for estimating the probability of adverse drug reactions
    • 8,120
    Hematologic Consequences of Poisoning
    • 6
    Drugdex System
    • Englewood, CO: Micromedex, Inc.
    • 2004
    Phenazopyridine-induced sulfhemoglobinemia (abstract)
    • J Toxicol Clin Toxicol
    • 2003