Phenazepam abuse in the UK: an emerging problem causing serious adverse health problems, including death

  title={Phenazepam abuse in the UK: an emerging problem causing serious adverse health problems, including death},
  author={J. Corkery and F. Schifano and A. Ghodse},
  journal={Human Psychopharmacology: Clinical and Experimental},
  • J. Corkery, F. Schifano, A. Ghodse
  • Published 2012
  • Medicine
  • Human Psychopharmacology: Clinical and Experimental
  • OBJECTIVE Phenazepam (fenazepam; 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; PNZ, 'Bonsai') is a benzodiazepine developed in the former Soviet Union during the 1970s to treat neurological disorders, epilepsy, and alcohol withdrawal syndrome. [...] Key Result Although first use was reported in the UK in October 2009, major concerns in the UK arose in summer 2010 when individuals across Britain were admitted to hospital following overdose.Expand Abstract
    36 Citations
    Detection of phenazepam in impaired driving.
    • 13
    • PDF
    5-(2-Aminopropyl)benzofuran and phenazepam demonstrate the possibility of dependence by increasing dopamine levels in the brain
    • 7
    Phenazepam: More information coming in from the cold.
    • 12
    • PDF
    Novel psychoactive substances of interest for psychiatry
    • 157
    • PDF
    Bridging the gap between education and appropriate use of benzodiazepines in psychiatric clinical practice
    • 35
    • PDF
    Analysis of phenazepam and 3-hydroxyphenazepam in post-mortem fluids and tissues.
    • 20
    • PDF


    Phenazepam is currently being misused in the UK
    • 16
    • PDF
    Addiction: Part I. Benzodiazepines--side effects, abuse risk and alternatives.
    • 274
    Fatality involving the ingestion of phenazepam and poppy seed tea.
    • 37
    • Highly Influential
    • PDF
    Phenazepam - a new drug of abuse in Finland - findings from apprehended drivers
    • 4
    • Highly Influential
    • PDF
    [The pharmacokinetic characteristics of fenazepam in epileptics].
    • 6
    Mephedrone (4-methylmethcathinone; ‘meow meow’): chemical, pharmacological and clinical issues
    • 276
    • PDF
    Modulation of GABAA receptor-mediated currents by phenazepam and its metabolites
    • 12
    Two UK suicides using nicotine extracted from tobacco employing instructions available on the Internet.
    • 38
    • PDF
    Species differences in phenazeram kinetics and metabolism
    • 25
    • Highly Influential
    Trauma and substance abuse: deadly consequences of intravenous percocet tablets.
    • 4