Phasic visual alertness in Alzheimer's disease and ageing.

@article{Tales2002PhasicVA,
  title={Phasic visual alertness in Alzheimer's disease and ageing.},
  author={Andrea Tales and Janice L. Muir and Antony Bayer and Roy A. L. Jones and Robert J. Snowden},
  journal={Neuroreport},
  year={2002},
  volume={13 18},
  pages={2557-60}
}
An individual's ability to see and react quickly to a target stimulus is enhanced if they are alerted to the arrival of this target by a stimulus that occurs just prior in time to it. This alerting effect is thought to occur due to a phasic increase in alertness mediated by noradrenergic activity. In Alzheimer's disease (AD) there is a dysfunction in the noradrenergic system resulting in a decrease in central levels of noradrenaline. We therefore predicted that patients with AD would not be… CONTINUE READING

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Acknowledgements:This project was fundedby an Alzheimer’s Society Research Fellowship to A.T

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