Phase transitions and size scaling of membrane-less organelles

  title={Phase transitions and size scaling of membrane-less organelles},
  author={Clifford P Brangwynne},
  booktitle={The Journal of cell biology},
The coordinated growth of cells and their organelles is a fundamental and poorly understood problem, with implications for processes ranging from embryonic development to oncogenesis. Recent experiments have shed light on the cell size-dependent assembly of membrane-less cytoplasmic and nucleoplasmic structures, including ribonucleoprotein (RNP) granules and other intracellular bodies. Many of these structures behave as condensed liquid-like phases of the cytoplasm/nucleoplasm. The phase… CONTINUE READING
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