Phase transitions and permeability changes in dry membranes during rehydration.

  title={Phase transitions and permeability changes in dry membranes during rehydration.},
  author={John H. Crowe and Lois M. Crowe and Folkert A. Hoekstra},
  journal={Journal of bioenergetics and biomembranes},
  volume={21 1},
Dry phospholipid bilayers are known to undergo transient changes in permeability during rehydration. In this review, we present evidence from which we suggest that this permeability change is due to a gel to liquid-crystalline phase transition accompanying rehydration. If the transition is avoided, as in lipids that remain in gel phase whether dry or rehydrated, the problem of leakage during rehydration is obviated, at least in part. Further, the evidence that the transition temperature for dry… CONTINUE READING

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