Phase-transition thresholds and vaporization phenomena for ultrasound phase-change nanoemulsions assessed via high-speed optical microscopy.

@article{Sheeran2013PhasetransitionTA,
  title={Phase-transition thresholds and vaporization phenomena for ultrasound phase-change nanoemulsions assessed via high-speed optical microscopy.},
  author={Paul S. Sheeran and Terry Onichi Matsunaga and Paul A. Dayton},
  journal={Physics in medicine and biology},
  year={2013},
  volume={58 13},
  pages={4513-34}
}
Ultrasonically activated phase-change contrast agents (PCCAs) based on perfluorocarbon droplets have been proposed for a variety of therapeutic and diagnostic clinical applications. When generated at the nanoscale, droplets may be small enough to exit the vascular space and then be induced to vaporize with high spatial and temporal specificity by externally-applied ultrasound. The use of acoustical techniques for optimizing ultrasound parameters for given applications can be a significant… CONTINUE READING

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