Phase tracking: an improved phase detection technique for cell membrane capacitance measurements.

@article{Fidler1989PhaseTA,
  title={Phase tracking: an improved phase detection technique for cell membrane capacitance measurements.},
  author={N Fidler and J. M. Fern{\'a}ndez},
  journal={Biophysical journal},
  year={1989},
  volume={56 6},
  pages={1153-62}
}
We describe here a technique called phase tracking that greatly improves the accuracy of measurements of the membrane capacitance of single cells. We have modified the original phase detection technique to include a method for creating calibrated changes in the resistance in series with the cell. This provides a method to automate the adjustment of the phase detector to the appropriate phase angle for measuring membrane capacitance. The phase determination depends only on the cell's electrical… CONTINUE READING