Phase separation in bilayer lipid membranes: effects on the inner leaf due to coupling to the outer leaf.

Abstract

The combined effects of the tendency of cholesterol to order lipids in the liquid phase and the coupling between lipids in the two leaves of a bilayer are investigated theoretically utilizing a Landau free energy. We show that as a consequence of these combined effects, lateral phase separation in the outer leaf between cholesterol-rich and -poor liquids… (More)

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