Phase plates for transmission electron microscopy.

  title={Phase plates for transmission electron microscopy.},
  author={Radostin Danev and Kuniaki Nagayama},
  journal={Methods in enzymology},
Phase plates are a new technique in the field of cryo-electron microscopy. They provide improved contrast and signal-to-noise ratio in images of radiation sensitive specimens. Thin film phase plates are being tested in biological applications and have demonstrated benefits for single particle analysis and cryo-tomography. There are still unsolved problems, such as reliability of manufacturing and deterioration of performance with time. Several other types of phase plates are currently under… CONTINUE READING

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