Phase behavior of an equimolar mixture of N-palmitoyl-D-erythro-sphingosine, cholesterol, and palmitic acid, a mixture with optimized hydrophobic matching.

@article{Brief2009PhaseBO,
  title={Phase behavior of an equimolar mixture of N-palmitoyl-D-erythro-sphingosine, cholesterol, and palmitic acid, a mixture with optimized hydrophobic matching.},
  author={Elana E Brief and Sungjong Kwak and John T-J Cheng and Neil Kitson and Jenifer L Thewalt and Michel Lafleur},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2009},
  volume={25 13},
  pages={7523-32}
}
The phase behavior and lipid mixing properties of an equimolar mixture of nonhydroxylated palmitoyl ceramide (Cer16), palmitic acid (PA), and cholesterol have been investigated using 2H NMR and vibrational spectroscopy. This mixture is formed by the three main classes of lipids found in the stratum corneum (SC), the top layer of the epidermis, and provides an optimized hydrophobic matching. Therefore, its behavior highlights the role played by hydrophobic matching on the phase behavior of SC… CONTINUE READING

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