Phase-adjustment of human circadian rhythms by light and physical exercise

@article{Yamanaka2016PhaseadjustmentOH,
  title={Phase-adjustment of human circadian rhythms by light and physical exercise},
  author={Yujiro Yamanaka and James M. Waterhouse},
  journal={The Journal of Physical Fitness and Sports Medicine},
  year={2016},
  volume={5},
  pages={287-299}
}
The human circadian system derives from two distinct circadian oscillators that separately regulate circadian rhythms of body temperature and plasma melatonin, and of the sleep-wake cycle. The oscillator for body temperature and melatonin is the central circadian pacemaker, located in the hypothalamic suprachiasmatic nucleus (SCN), and the oscillator for sleep-wake cycle is another oscillator, located in the brain but outside the SCN. Although bright light is a primary zeitgeber for circadian… 
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References

SHOWING 1-10 OF 68 REFERENCES

Differential regulation of circadian melatonin rhythm and sleep-wake cycle by bright lights and nonphotic time cues in humans.

Polysomnographical analyses revealed that deterioration of sleep quality by shift schedule was protected by physical exercise under bright lights, indicating differential regulation of sleep-wake cycle and circadian melatonin rhythm by physical Exercise in humans.

Daily exercise facilitates phase delays of circadian melatonin rhythm in very dim light.

The data suggest that exercise may help to facilitate circadian adaptation to schedules requiring a delay in the sleep-wake cycle, and that the closer to the DLMO(25%), the greater the phase shift.

Seasonal variation in the human circadian rhythm: dissociation between sleep and temperature rhythm.

Findings indicate that not only the external (to the local time) but also the internal (between circadian rhythms) phase relations of the human circadian rhythms depend on season.

Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans

  • D.G.M. DijkC. Czeisler
  • Biology, Psychology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1995
Analyses of the (nonadditive) interaction of the circadian and sleep-dependent components of sleep propensity and sleep structure revealed that the phase relation between the sleep-wake cycle and the circadian pacemaker during entrainment promotes the consolidation of sleep and wakefulness and facilitates the transitions between these vigilance states.

Light and plasma melatonin rhythm in humans.

It is concluded that the plasma melatonin rhythm is the best marker of the human circadian pacemaker so far available.

Entrainment of the circadian clock in the liver by feeding.

It is demonstrated that feeding cycles can entrain the liver independently of the SCN and the light cycle, and the need to reexamine the mammalian circadian hierarchy is suggested, raising the possibility that peripheral circadian oscillators like those in the liver may be coupled to theSCN primarily through rhythmic behavior, such as feeding.

Non-photic entrainment of human rest-activity cycle independent of circadian pacemaker

It is concluded that non-photic zeitgebers can entrain the rest-activity cycle in humans, which is independent of the circadian pacemaker.

Scheduled exercise phase shifts the circadian clock in skeletal muscle.

Evidence is provided that the molecular circadian clock in peripheral tissues can respond to the time of exercise suggesting that physical activity contributes important timing information for synchronization of circadian clocks throughout the body.

Rapid down-regulation of mammalian period genes during behavioral resetting of the circadian clock.

Circadian oscillations of Per1 and Per2 in the SCN of the Syrian hamster are described, showing that PER1 protein and mRNA cycles again behave in a manner consistent with a negative-feedback oscillator, and it is demonstrated that nonphotic resetting has the opposite effect to light: acutely down-regulating these genes.

Resetting central and peripheral circadian oscillators in transgenic rats.

It is hypothesize that a self-sustained circadian pacemaker in the SCN entrains circadian oscillators in the periphery to maintain adaptive phase control, which is temporarily lost following large, abrupt shifts in the environmental light cycle.
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