Phase Resetting Reveals Network Dynamics Underlying a Bacterial Cell Cycle

@article{Lin2012PhaseRR,
  title={Phase Resetting Reveals Network Dynamics Underlying a Bacterial Cell Cycle},
  author={Yihan Lin and Y. Li and Sean Crosson and Aaron R. Dinner and Norbert F. Scherer},
  journal={PLoS Computational Biology},
  year={2012},
  volume={8}
}
Genomic and proteomic methods yield networks of biological regulatory interactions but do not provide direct insight into how those interactions are organized into functional modules, or how information flows from one module to another. In this work we introduce an approach that provides this complementary information and apply it to the bacterium Caulobacter crescentus, a paradigm for cell-cycle control. Operationally, we use an inducible promoter to express the essential transcriptional… 

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