Phase II study of gemcitabine plus S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy.

@article{Peng2016PhaseIS,
  title={Phase II study of gemcitabine plus S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy.},
  author={Peijian Peng and XueQing Ou and Hai Liao and Yumeng Liu and Siyang Wang and Zhibin Cheng and Zhong Qiu Lin},
  journal={Therapeutic advances in medical oncology},
  year={2016},
  volume={8 3},
  pages={153-9}
}
PURPOSE No standard salvage regimen has been established for patients with recurrent and metastatic nasopharyngeal carcinoma (NPC) and disease progression after prior platinum-based chemotherapy. This phase II study was designed to evaluate the efficacy and safety of gemcitabine plus S-1 (GS) chemotherapy as a remedial regimen in this setting. METHODS In this multicenter phase II study, 49 patients with recurrent and metastatic NPC who failed previous platinum-based chemotherapy received… CONTINUE READING

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