Phase II study of first-line sequential chemotherapy with gemcitabine-carboplatin followed by docetaxel in patients with advanced non-small cell lung cancer.

@article{Chiappori2005PhaseIS,
  title={Phase II study of first-line sequential chemotherapy with gemcitabine-carboplatin followed by docetaxel in patients with advanced non-small cell lung cancer.},
  author={Alberto Alejandro Chiappori and George Rajan Simon and Charles C. Williams and Eric B. Haura and Caio Max S Rocha-Lima and Henry Wagner and Gerold Bepler and Scott J. Antonia},
  journal={Oncology},
  year={2005},
  volume={68 4-6},
  pages={382-90}
}
RATIONALE Despite the use of novel chemotherapeutic agents, patients with advanced non-small cell lung cancer (NSCLC) continue to show a poor survival. OBJECTIVES To assess the safety and efficacy of a novel sequential and putatively non-cross-resistant chemotherapy regimen. METHODS Eligibility included: stages IV and IIIB (malignant pleural effusion), performance status 0-1, and adequate renal, hepatic and bone marrow function. Patients with previously treated and controlled brain… CONTINUE READING

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