Phase II study of elsamitrucin in non-small cell lung cancer

@article{Goss2004PhaseIS,
  title={Phase II study of elsamitrucin in non-small cell lung cancer},
  author={G. Goss and F. Letendre and D. Stewart and F. Shepherd and L. Schacter and P. Hoogendoorn and E. Eisenhauer},
  journal={Investigational New Drugs},
  year={2004},
  volume={12},
  pages={315-317}
}
Elsamitrucin (BMY-28090) a novel fermentation product has demonstrated pre-clinical anti-tumour activity against a number of cell lines. The dose limiting toxicity in phase I studies was a reversible increase in hepatic transaminase. This study was initiated to determine the activity of elsamitrucin in patients with previously untreated, bi-dimensionally measurable, cytologically or histologically proven, non-small cell lung cancer who were not curable by surgery. Elsamitrucin at a dose of 25… Expand
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