Phase II safety and clinical comparison with single-photon emission computed tomography myocardial perfusion imaging for detection of coronary artery disease: flurpiridaz F 18 positron emission tomography.

@article{Berman2013PhaseIS,
  title={Phase II safety and clinical comparison with single-photon emission computed tomography myocardial perfusion imaging for detection of coronary artery disease: flurpiridaz F 18 positron emission tomography.},
  author={D. Berman and J. Maddahi and B. Tamarappoo and J. Czernin and R. Taillefer and J. Udelson and C. Gibson and M. Devine and J. Lazewatsky and G. Bhat and Dana Washburn},
  journal={Journal of the American College of Cardiology},
  year={2013},
  volume={61 4},
  pages={
          469-477
        }
}
  • D. Berman, J. Maddahi, +8 authors Dana Washburn
  • Published 2013
  • Medicine
  • Journal of the American College of Cardiology
  • OBJECTIVES This was a phase II trial to assess flurpiridaz F 18 for safety and compare its diagnostic performance for positron emission tomography (PET) myocardial perfusion imaging (MPI) with Tc-99m single-photon emission computed tomography (SPECT) MPI with regard to image quality, interpretative certainty, defect magnitude, and detection of coronary artery disease (CAD) (≥50% stenosis) on invasive coronary angiography (ICA). BACKGROUND In pre-clinical and phase I studies, flurpiridaz F 18… CONTINUE READING
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    References

    SHOWING 1-10 OF 32 REFERENCES
    Diagnostic accuracy of rest/stress ECG-gated Rb-82 myocardial perfusion PET: Comparison with ECG-gated Tc-99m sestamibi SPECT
    • T. Bateman, G. Heller, +7 authors S. Cullom
    • Medicine
    • Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
    • 2006
    • 454
    • PDF
    Detection of coronary artery disease with perfusion stress echocardiography using a novel ultrasound imaging agent: two Phase 3 international trials in comparison with radionuclide perfusion imaging.
    • R. Senior, M. Monaghan, +15 authors M. H. Picard
    • Medicine
    • European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology
    • 2009
    • 66
    • PDF
    Comparison of Clinical Tools for Measurements of Regional Stress and Rest Myocardial Blood Flow Assessed with 13N-Ammonia PET/CT
    • 90
    • PDF
    Properties of an ideal PET perfusion tracer: New PET tracer cases and data
    • J. Maddahi
    • Medicine
    • Journal of Nuclear Cardiology
    • 2012
    • 74
    BMS-747 158-02: A novel PET myocardial perfusion imaging agent
    • M. Yu, Mary Guaraldi, +8 authors S. Robinson
    • Medicine
    • Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
    • 2007
    • 128
    Noninvasive quantitation of myocardial blood flow in human subjects with oxygen-15-labeled water and positron emission tomography.
    • 438
    • PDF
    Initial Characterization of an 18F-Labeled Myocardial Perfusion Tracer
    • 128
    • PDF