Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors.

@article{Muragaki2013PhaseIC,
  title={Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors.},
  author={Yoshihiro Muragaki and Jiro Akimoto and Takashi Maruyama and Hiroshi Iseki and Soko Ikuta and M. Nitta and Katsuya Maebayashi and Taiichi Saito and Yoshikazu Okada and Sadao Kaneko and Akira Matsumura and Toshihiko Kuroiwa and Katsuyuki Karasawa and Yoichi Nakazato and Takamasa Kayama},
  journal={Journal of neurosurgery},
  year={2013},
  volume={119 4},
  pages={
          845-52
        }
}
OBJECT The objective of the present study was to perform a prospective evaluation of the potential efficacy and safety of intraoperative photodynamic therapy (PDT) using talaporfin sodium and irradiation using a 664-nm semiconductor laser in patients with primary malignant parenchymal brain tumors. METHODS In 27 patients with suspected newly diagnosed or recurrent primary malignant parenchymal brain tumors, a single intravenous injection of talaporfin sodium (40 mg/m(2)) was administered 1… CONTINUE READING
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