Phase I trial of oxaliplatin in combination with cisplatin, protacted-infusion fluorouracil, and radiotherapy in advanced esophageal and gastroesophageal carcinoma.

Abstract

PURPOSE To define the maximum-tolerated dose of oxaliplatin given with cisplatin, protacted 96-h infusion of fluorouracil, and radiotherapy for patients with advanced esophageal cancer. PATIENTS AND METHODS Seventeen patients with locally advanced esophageal cancer and 2 patients with local recurrence were treated. Escalating doses of oxaliplatin… (More)

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@article{Maurel2005PhaseIT, title={Phase I trial of oxaliplatin in combination with cisplatin, protacted-infusion fluorouracil, and radiotherapy in advanced esophageal and gastroesophageal carcinoma.}, author={Joan Maurel and Andres A P Cervantes and Carlos Conill and R Salazar and Marta Mart{\'i}n-Richard and Manuel Pera and Hermini Manzano and Isabel Chirivella and Rosa Gallego and Xavier Marf{\`a}}, journal={International journal of radiation oncology, biology, physics}, year={2005}, volume={62 1}, pages={91-6} }