Phase I clinical trial of safety of L-serine for ALS patients

@article{Levine2017PhaseIC,
  title={Phase I clinical trial of safety of L-serine for ALS patients},
  author={Todd D. Levine and Robert G. Miller and Walter G Bradley and D. Moore and David S. Saperstein and Lynne E Flynn and Jonathan S. Katz and Dallas A. Forshew and James S Metcalf and Sandra Anne Banack and Paul Alan Cox},
  journal={Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration},
  year={2017},
  volume={18},
  pages={107 - 111}
}
Abstract We performed a randomized, double-blind phase I clinical trial for six months on the effects of oral L-serine in patients with ALS. The protocol called for enrollment of patients with a diagnosis of probable or definite ALS, age 18–85 years, disease duration of less than three years and forced vital capacity (FVC) ≥ 60%. Patients were randomly assigned to four different oral twice-daily dose regimens (0.5, 2.5, 7.5, or 15 g/dose). Blood, urine and CSF samples, ALS Functional Rating… 
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