Phase I clinical trial and pharmacokinetics of intravesical mitomycin C in dogs with localized transitional cell carcinoma of the urinary bladder.

Abstract

BACKGROUND Transitional cell carcinoma (TCC) is the most common cancer of the urinary tract in dogs. The most frequent cause of death is urinary obstruction from the primary tumor. Standard medical therapy for TCC is only partially effective. HYPOTHESIS/OBJECTIVES Intravesical administration of mitomycin C (MMC) in dogs with invasive TCC will result in… (More)
DOI: 10.1111/j.1939-1676.2010.0569.x

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