Phase I and II trial on infusional 5-fluorouracil and gefitinib in combination with preoperative radiotherapy in rectal cancer: 10-years median follow-up

@inproceedings{Gambacorta2018PhaseIA,
  title={Phase I and II trial on infusional 5-fluorouracil and gefitinib in combination with preoperative radiotherapy in rectal cancer: 10-years median follow-up},
  author={Maria Antonietta Gambacorta and Antonino De Paoli and Marco Lupattelli and Giuditta Chiloiro and Angela Pia Solazzo and Brunella Barbaro and Sergio Alfieri and Fabio Maria Vecchio and Jacopo Lenkowicz and Francesco Navarria and Elisa Palazzari and Giulio Bertola and Alessandro Frattegiani and Bruce Daniel Minsky and Vincenzo Valentini},
  booktitle={Clinical and translational radiation oncology},
  year={2018}
}
Purpose The aim of this study is to evaluate the long term survival of the addition of gefitinib to chemoradiotherapy (CRT) in locally advanced rectal cancer (LARC). Methods and materials This previously published multicentre, open-label, phase I-II study, enrolled patients (pts) with LARC to receive CRT with concurrent 5-fluorouracil continuous… CONTINUE READING