Phase I/II trial of the safety and efficacy of shark cartilage in the treatment of advanced cancer.

Abstract

PURPOSE Patients with cancer and chronic inflammatory disorders have used shark cartilage (SC) preparations for many years. Preclinical studies that support their beneficial effects are scanty, and reports of clinical trials have been anecdotal. The proposed mechanisms of antitumor action include direct or indirect inhibition of angiogenesis. Because of the… (More)

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@article{Miller1998PhaseIT, title={Phase I/II trial of the safety and efficacy of shark cartilage in the treatment of advanced cancer.}, author={D. Richard Miller and Grant T Anderson and Josef Stark and Jennifer L. Granick and Debra Richardson}, journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology}, year={1998}, volume={16 11}, pages={3649-55} }