Phase I/II trial of paclitaxel by 1-hour infusion, carboplatin, and gemcitabine in the treatment of patients with advanced nonsmall cell lung carcinoma.

@article{Hainsworth1999PhaseIT,
  title={Phase I/II trial of paclitaxel by 1-hour infusion, carboplatin, and gemcitabine in the treatment of patients with advanced nonsmall cell lung carcinoma.},
  author={John D Hainsworth and Howard A. Burris and Joan B Erland and Lisa H Morrissey and Anthony A Meluch and Leonard A Kalman and Jeremy K Hon and Daniel C Scullin and Stephanie W Smith and Frank Anthony Greco},
  journal={Cancer},
  year={1999},
  volume={85 6},
  pages={1269-76}
}
BACKGROUND The combination of paclitaxel and carboplatin is widely used in the treatment of patients with advanced nonsmall cell lung carcinoma. In this Phase I/II study the authors evaluated the feasibility, toxicity, and efficacy of adding a third active antineoplastic agent, gemcitabine, to the paclitaxel/carboplatin combination for the treatment of patients with advanced nonsmall cell lung carcinoma. METHODS Patients with advanced (AJCC Stage IIIB or IV) nonsmall cell lung carcinoma… CONTINUE READING