Phase I/II study of docetaxel and S-1 in patients with previously treated non-small cell lung cancer.

@article{Atagi2008PhaseIS,
  title={Phase I/II study of docetaxel and S-1 in patients with previously treated non-small cell lung cancer.},
  author={Shinji Atagi and Masaaki Kawahara and Yoko Kusunoki and Minoru Takada and Tomoya Kawaguchi and Kyoiti Okishio and Akihito Kubo and Kazutaka Uehira and Katsuyuki Yumine and Yoshio Tomizawa and Ryusei Saito and Shimao Fukai and Hikotaro Komatsu},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2008},
  volume={3 9},
  pages={1012-7}
}
INTRODUCTION The aim of this study was to determine and evaluate the recommended dose of docetaxel in combination with a novel oral 5-fluorouracil analogue S-1 and evaluate the efficacy and safety in patients with previously treated non-small cell lung cancer. METHODS In phase I, patients with previously treated non-small cell lung cancer were treated with docetaxel (starting dose 40 mg/m) intravenously on day 1 and oral administration of S-1 at a fixed dose of 80 mg/m on days 1 to14 every 3… CONTINUE READING
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