Phase 2 trial of maintenance bevacizumab alone after bevacizumab plus pemetrexed and carboplatin in advanced, nonsquamous nonsmall cell lung cancer.

@article{Stevenson2012Phase2T,
  title={Phase 2 trial of maintenance bevacizumab alone after bevacizumab plus pemetrexed and carboplatin in advanced, nonsquamous nonsmall cell lung cancer.},
  author={James P. Stevenson and Corey J. Langer and Robert A. Somer and Tracey L. Evans and Kumar Rajagopalan and Kimberly Krieger and Mona Jacobs-Small and Nikolas Dyanick and Barry Milcarek and Susan Coakley and Suzanne I. Walker and Beth Eaby-Sandy and Alexandre Hageboutros},
  journal={Cancer},
  year={2012},
  volume={118 22},
  pages={5580-7}
}
BACKGROUND The authors performed a phase 2 study of bevacizumab plus pemetrexed and carboplatin followed by maintenance bevacizumab in patients with advanced, nonsquamous nonsmall cell lung cancer. METHODS Previously untreated patients with advanced, nonsquamous nonsmall cell lung cancer and an Eastern Cooperative Oncology Group performance status of 0 or 1 received bevacizumab 15 mg/kg, pemetrexed 500 mg/m(2) and carboplatin at an area under the concentration-time curve of 6 intravenously on… CONTINUE READING
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