Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults

@article{Mulligan2020PhaseIS,
  title={Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults},
  author={M. Mulligan and K. Lyke and N. Kitchin and J. Absalon and A. Gurtman and S. Lockhart and K. Neuzil and Vanessa N Raabe and Ruth Bailey and Kena A Swanson and P. Li and Kenneth Koury and Warren Kalina and D. Cooper and C. Fontes-Garfias and Pei-Yong Shi and {\"O}. T{\"u}reci and K. Tompkins and E. Walsh and R. Frenck and A. Falsey and P. R. Dormitzer and W. Gruber and U. Şahin and K. Jansen},
  journal={Nature},
  year={2020},
  pages={1-5}
}
  • M. Mulligan, K. Lyke, +22 authors K. Jansen
  • Published 2020
  • Medicine
  • Nature
  • In March 2020, the World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 1 , a pandemic. With rapidly accumulating numbers of cases and deaths reported globally 2 , a vaccine is urgently needed. Here we report the available safety, tolerability and immunogenicity data from an ongoing placebo-controlled, observer-blinded dose-escalation study (ClinicalTrials.gov identifier NCT04368728) among… CONTINUE READING
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