Pharmacotherapy of lower limb diabetic ulcers.

  title={Pharmacotherapy of lower limb diabetic ulcers.},
  author={Mary E. Temple and Milap C. Nahata},
  journal={Journal of the American Geriatrics Society},
  volume={48 7},
OBJECTIVE To discuss the pathophysiology, microbiology, and pharmacotherapy of lower extremity (LE) diabetic ulcers. DATA SOURCES A MEDLINE search from 1966 to April 1999 was conducted. The search was limited to humans and English-language journals. Key search words included "diabetic ulcer," "fluoroquinolones," "beta-lactam," "hyperbaric oxygen," "diabetes mellitus," "diabetic foot," and "growth factor." STUDY SELECTION Randomized and nonrandomized studies were selected for review. Results… CONTINUE READING

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