Pharmacotherapy for posttraumatic stress disorder: A status report

@article{Friedman1998PharmacotherapyFP,
  title={Pharmacotherapy for posttraumatic stress disorder: A status report},
  author={Matthew J. Friedman},
  journal={Psychiatry and Clinical Neurosciences},
  year={1998},
  volume={52}
}
  • M. Friedman
  • Published 1 September 1998
  • Psychology, Biology
  • Psychiatry and Clinical Neurosciences
Pharmacotherapy for posttraumatic stress disorder (PTSD) appears to be a promising approach because many neurobiological systems appear to be altered in PTSD patients. This review encompasses the current published literature on clinical trials with antiadrenergic agents (propranolol, clonidine, guanfacine), selective serotonin reuptake inhibitors (SSRI), other serotonergic agents, monoamine oxidase inhibitors (MAOI), tricyclic antidepressants (TCA), benzodiazepines, anticonvulsants, narcotic… 
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Fluoxetine is an effective pharmacotherapeutic agent for treating PTSD and its associated features, particularly in patients without chronic treatment histories, and non-VA patients responded much better than VA patients.
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