Pharmacotherapies for obstructive sleep apnea: how close are we?

  title={Pharmacotherapies for obstructive sleep apnea: how close are we?},
  author={Sigrid Carlen Veasey},
  journal={Current opinion in pulmonary medicine},
  volume={7 6},
Obstructive sleep apnea is a prevalent disorder associated with significant neurobehavioral and cardiovascular morbidities. At present, however, there are no widely effective, well-tolerated pharmacotherapies for obstructive sleep apnea. The pathogenesis of this disorder predicts that sleep apnea should respond to drug therapies. Specifically, respiration during waking in persons with sleep apnea is normal, while collapse of the upper airway occurs exclusively in sleep. This state-dependency in… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 13 extracted citations

The tongue and its control by sleep state-dependent modulators.

Archives italiennes de biologie • 2011
View 1 Excerpt

Neuromodulation of hypoglossal motoneurons during sleep

Respiratory Physiology & Neurobiology • 2008
View 1 Excerpt

Similar Papers

Loading similar papers…