Pharmacoprophylaxis of alcohol dependence: Review and update Part I: Pharmacology

  title={Pharmacoprophylaxis of alcohol dependence: Review and update Part I: Pharmacology},
  author={Sandeep Grover and Gaurav Bhateja and Debasish Basu},
  booktitle={Indian journal of psychiatry},
Alcohol dependence is a major problem in India. The pharmacological armamentarium for relapse prevention of alcohol has widened with the addition of new drugs. In this article, we review the pharmacology and efficacy of the four most important such drugs: disulfiram, naltrexone, acamprosate and topiramate. The first part of this two-part review series concerns the comparative pharmacology and the second part concerns the efficacy studies. Overall, all four of these drugs have modest but… CONTINUE READING