Pharmacophore modelling, virtual screening and molecular docking studies on PLD1 inhibitors.


Lipid metabolism plays a significant role in influenza virus replication and subsequent infection. The regulatory mechanism governing lipid metabolism and viral replication is not properly understood to date, but both Phospholipase D (PLD1 and PLD2) activities are stimulated in viral infection. In vitro studies indicate that chemical inhibition of PLD1… (More)
DOI: 10.1080/1062936X.2017.1393774


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