Corpus ID: 100223758

Pharmacology of prooxen

@article{Vv1980PharmacologyOP,
  title={Pharmacology of prooxen},
  author={Vinogradov Vv and Krylov Ss},
  journal={Farmakologiia i toksikologiia},
  year={1980},
  volume={43},
  pages={563}
}
Prooxen--9-(3-dimethylaminopropyliden) xanthene--administered in small doses (0.05-0.1 mg/kg) produces a central and peripheral adrenosensibilizing effect, diminishes the duration of hexenal sleep, disturbs the differentiation, and causes appearance of intersignal reactions in experiments with conditioned reflexes. The drug exerts an antireserpine action. In large doses (5 mg/kg and over) it displays a tranquilizing action, prolongs the narcotic action of hexenal and chloral hydrate. LD50 and… Expand